Nogapendekin alfa
Nogapendekin alfa is a protein pharmaceutical. It is currently being investigated in clinical studies.
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Commercial
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Drug Products
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New Drug Application (NDA)
New Drug Application (NDA)
Abbreviated New Drug Application (ANDA)
Abbreviated New Drug Application (ANDA)
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Labels
FDA
EMA
Brand Name | Status | Last Update |
|---|---|---|
| anktiva | Biologic Licensing Application | 2024-05-09 |
Indications
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Agency Specific
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Clinical
Clinical Trials
74 clinical trials
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Indications Phases 4
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Indications Phases 3
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Carcinoma | D002277 | — | C80.0 | 7 | 12 | 1 | — | — | 13 |
| Non-small-cell lung carcinoma | D002289 | — | — | 3 | 7 | 2 | — | — | 8 |
| Lung neoplasms | D008175 | HP_0100526 | C34.90 | 4 | 8 | 1 | — | — | 8 |
| Urinary bladder neoplasms | D001749 | — | C67 | 1 | 2 | 1 | — | 1 | 3 |
| Non-muscle invasive bladder neoplasms | D000093284 | — | — | 1 | 2 | 1 | — | 1 | 3 |
Indications Phases 2
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Pancreatic neoplasms | D010190 | EFO_0003860 | C25 | 6 | 7 | — | — | — | 8 |
| Squamous cell carcinoma | D002294 | — | — | 4 | 6 | — | — | — | 7 |
| Squamous cell carcinoma of head and neck | D000077195 | — | — | 3 | 6 | — | — | — | 7 |
| Myeloid leukemia acute | D015470 | — | C92.0 | 3 | 6 | — | — | — | 7 |
| Hiv infections | D015658 | EFO_0000764 | B20 | 6 | 2 | — | — | — | 7 |
| Colorectal neoplasms | D015179 | — | — | 3 | 6 | — | — | — | 6 |
| Leukemia | D007938 | — | C95 | 3 | 5 | — | — | — | 6 |
| Neoplasms | D009369 | — | C80 | 5 | 3 | — | — | — | 5 |
| Breast neoplasms | D001943 | EFO_0003869 | C50 | 4 | 5 | — | — | — | 5 |
| Lymphoma | D008223 | — | C85.9 | 5 | 3 | — | — | — | 5 |
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Indications Phases 1
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Healthy volunteers/patients | — | — | — | 2 | — | — | — | — | 2 |
| Hodgkin disease | D006689 | — | C81 | 2 | — | — | — | — | 2 |
| Covid-19 | D000086382 | — | — | 1 | — | — | — | — | 1 |
| Immunologic deficiency syndromes | D007153 | HP_0002721 | D84.9 | 1 | — | — | — | — | 1 |
| Myeloproliferative disorders | D009196 | — | D47.1 | 1 | — | — | — | — | 1 |
| Sarcoma | D012509 | — | — | 1 | — | — | — | — | 1 |
| Adenocarcinoma | D000230 | — | — | 1 | — | — | — | — | 1 |
| Ewing sarcoma | D012512 | EFO_0000173 | — | 1 | — | — | — | — | 1 |
| Rhabdomyosarcoma | D012208 | — | — | 1 | — | — | — | — | 1 |
Indications Without Phase
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Pharmacokinetics | D010599 | — | — | — | — | — | — | 1 | 1 |
| Invasive hydatidiform mole | D002820 | — | D39.2 | — | — | — | — | 1 | 1 |
Epidemiology
Epidemiological information for investigational and approved indications
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Drug
General
| Drug common name | Nogapendekin alfa |
| INN | nogapendekin alfa |
| Description | Nogapendekin alfa is a protein pharmaceutical. It is currently being investigated in clinical studies. |
| Classification | Protein |
| Drug class | interleukins |
| Image (chem structure or protein) |  |
| Structure (InChI/SMILES or Protein Sequence) | — |
Identifiers
| PDB | — |
| CAS-ID | — |
| RxCUI | — |
| ChEMBL ID | CHEMBL4297690 |
| ChEBI ID | — |
| PubChem CID | — |
| DrugBank | — |
| UNII ID | 7TK323DLA0 (ChemIDplus, GSRS) |
Target
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Trends
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Safety
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Adverse Events
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