Nogapendekin alfa
Nogapendekin alfa is a protein pharmaceutical. It is currently being investigated in clinical studies.
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Commercial
Therapeutic Areas
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Trade Name
FDA
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Drug Products
FDA
EMA
New Drug Application (NDA)
New Drug Application (NDA)
Abbreviated New Drug Application (ANDA)
Abbreviated New Drug Application (ANDA)
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Labels
FDA
EMA
Brand Name | Status | Last Update |
|---|---|---|
| anktiva | Biologic Licensing Application | 2025-06-24 |
Indications
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Agency Specific
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Patent Expiration
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ATC Codes
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HCPCS
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Clinical
Clinical Trials
89 clinical trials
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Indications Phases 4
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Indications Phases 3
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Non-small-cell lung carcinoma | D002289 | — | — | 3 | 8 | 3 | — | — | 10 |
| Non-muscle invasive bladder neoplasms | D000093284 | — | — | 1 | 3 | 1 | — | 1 | 4 |
| Lung neoplasms | D008175 | — | C34.90 | 1 | 3 | 1 | — | — | 3 |
| Urinary bladder neoplasms | D001749 | — | C67 | 1 | 2 | 1 | — | — | 2 |
Indications Phases 2
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Neoplasms | D009369 | — | C80 | 8 | 6 | — | — | — | 9 |
| Pancreatic neoplasms | D010190 | EFO_0003860 | C25 | 6 | 7 | — | — | — | 8 |
| Myeloid leukemia acute | D015470 | — | C92.0 | 3 | 6 | — | — | — | 7 |
| Colorectal neoplasms | D015179 | — | — | 3 | 6 | — | — | — | 6 |
| Squamous cell carcinoma of head and neck | D000077195 | — | — | 2 | 5 | — | — | — | 6 |
| Hiv infections | D015658 | EFO_0000764 | B20 | 5 | 2 | — | — | — | 6 |
| Hiv | D006678 | — | O98.7 | 5 | 2 | — | — | — | 6 |
| Carcinoma | D002277 | — | C80.0 | 5 | 5 | — | — | — | 5 |
| Breast neoplasms | D001943 | EFO_0003869 | C50 | 4 | 5 | — | — | — | 5 |
| Acquired immunodeficiency syndrome | D000163 | EFO_0000765 | B20 | 4 | 2 | — | — | — | 5 |
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Indications Phases 1
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Healthy volunteers/patients | — | — | — | 2 | — | — | — | — | 2 |
| Neoplasm metastasis | D009362 | EFO_0009708 | — | 2 | — | — | — | — | 2 |
| Covid-19 | D000086382 | — | U07.1 | 1 | — | — | — | — | 1 |
| Immunologic deficiency syndromes | D007153 | — | D84.9 | 1 | — | — | — | — | 1 |
| Myeloproliferative disorders | D009196 | — | D47.1 | 1 | — | — | — | — | 1 |
| Sarcoma | D012509 | — | — | 1 | — | — | — | — | 1 |
| Adenocarcinoma | D000230 | — | — | 1 | — | — | — | — | 1 |
| Ewing sarcoma | D012512 | EFO_0000173 | — | 1 | — | — | — | — | 1 |
| Rhabdomyosarcoma | D012208 | — | — | 1 | — | — | — | — | 1 |
| Syndrome | D013577 | — | — | 1 | — | — | — | — | 1 |
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Indications Without Phase
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Pharmacokinetics | D010599 | — | — | — | — | — | — | 1 | 1 |
| Invasive hydatidiform mole | D002820 | — | D39.2 | — | — | — | — | 1 | 1 |
| Lymphopenia | D008231 | — | D72.810 | — | — | — | — | 1 | 1 |
Epidemiology
Epidemiological information for investigational and approved indications
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Drug
General
| Drug common name | Nogapendekin alfa |
| INN | nogapendekin alfa |
| Description | Nogapendekin alfa is a protein pharmaceutical. It is currently being investigated in clinical studies. |
| Classification | Protein |
| Drug class | interleukins |
| Image (chem structure or protein) |  |
| Structure (InChI/SMILES or Protein Sequence) | — |
Identifiers
| PDB | — |
| CAS-ID | — |
| RxCUI | — |
| ChEMBL ID | CHEMBL4297690 |
| ChEBI ID | — |
| PubChem CID | — |
| DrugBank | — |
| UNII ID | 7TK323DLA0 (ChemIDplus, GSRS) |
Target
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Variants
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Financial
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Trends
PubMed Central
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Additional graphs summarizing 477 documents
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Safety
Black-box Warning
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Adverse Events
Top Adverse Reactions
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20 adverse events reported
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